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目的:分析并比较腹腔镜辅助与开腹手术治疗原发性胃肠道淋巴瘤(primary gastrointestinal lymphoma,PGIL)的短期及远期疗效。方法:收集2001年5月至2013年8月在我院行手术治疗的37例PGIL病人资料。其中腹腔镜组(LS组)22例,开腹组(OS组)15例。回顾性分析比较两组临床资料、手术相关资料、术后疗效及长期存活率等的差异。结果:37例中,胃淋巴瘤17例,小肠淋巴瘤15例,结肠直肠淋巴瘤5例。两组病人一般资料的比较及临床首要表现的差异无统计学意义;LS组的手术时间长于OS组,差异有统计学意义(P<0.05);LS组的术中出血量少于OS组,差异有统计学意义(P<0.05);淋巴结清扫数LS组多于OS组,差异有统计学意义(P<0.05)。LS组在术后恢复方面均显著优于OS组,差异有统计学意义。两组对病人远期生存率的影响无统计学意义。病人远期生存率主要与病理分期相关。结论:腹腔镜辅助PGIL切除术治疗PGIL安全、有效,短期疗效优于开腹手术,远期疗效与开腹手术相似。
Objective: To analyze and compare the short-term and long-term effects of laparoscopic assisted and open surgery in the treatment of primary gastrointestinal lymphoma (PGIL). Methods: Thirty-seven PGIL patients who underwent surgery in our hospital from May 2001 to August 2013 were collected. Among them, there were 22 cases of laparoscopic group (LS group) and 15 cases of laparotomy group (OS group). Retrospective analysis of two groups of clinical data, surgical data, postoperative efficacy and long-term survival rate differences. Results: In 37 cases, there were 17 cases of gastric lymphoma, 15 cases of small intestine lymphoma and 5 cases of colorectal lymphoma. There was no significant difference between the two groups in the general information and the primary clinical manifestations. The operative time in LS group was longer than that in OS group (P <0.05). The LS group had less intraoperative blood loss than OS group, The difference was statistically significant (P <0.05). The number of lymph node dissection in LS group was more than that in OS group (P <0.05). LS group was significantly better than OS group in postoperative recovery, the difference was statistically significant. The two groups had no significant effect on the long-term survival rate of patients. Long-term survival of patients with the main pathological stage. Conclusion: Laparoscopic-assisted PGIL resection is a safe and effective method for PGIL. Short-term curative effect is superior to laparotomy. The long-term curative effect is similar to that of laparotomy.