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目的观察东菱克栓酶（ＤＦ－５２１）超早期治疗急性脑梗塞的疗效。方法应用ＤＦ－５２１治疗急性脑梗塞１０７例，并与脉络宁治疗组对照。结果显示超早期（＜６小时）溶栓组的显效率和有效率在治疗后不同时期明显高于对照组；６～２４小时溶栓组仅１周末和１２周末的有效率高于对照组；而２４～７２小时和＞７２小时溶栓组的显效率和有效率与对照组比较无差异。结论ＤＦ－５２１治疗急性脑梗塞以超早期（＜６小时）使用最好；＞２４小时使用该药的疗效尚需进一步观察
Objective To observe the curative effect of DF-521 in the treatment of acute cerebral infarction. Methods 107 cases of acute cerebral infarction were treated with DF-521 and compared with Mailuoning treatment group. The results showed that in the early (<6 hours) thrombolytic group, the effective rate and the effective rate of the thrombolytic group were significantly higher than those of the control group at different stages after treatment; the effective rate of the thrombolytic group was only 1 week and 12 weeks after 6 ~ 24 hours; However, there was no difference between the effective rate and the effective rate of the thrombolytic group in 24 ~ 72 hours and> 72 hours. Conclusion DF-521 treatment of acute cerebral infarction in the very early (<6 hours) the best use;> 24 hours the use of the efficacy of the drug needs further observation