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本文总结了采用数字减影血管造影(DSA)介入栓塞技术治疗的6例颌骨中心性血管瘤病例,将采用此技术治疗后手术切除的组织进行病理学观察。结果显示:经介入治疗后,血管瘤腔窦内有血凝块,部分腔窦闭塞,血管内皮细胞变性、坏死(凝固性坏死为主)。局部纤维结缔组织增生,机化血凝块,并出现明显的炎症反应。电镜观察:介入治疗后,血管内皮细胞出现核固缩,胞浆水肿,空泡变性,线粒体水肿,细胞间失去正常的连结结构,细胞之间间隙增宽。证明数字减影血管造影(DSA)介入栓塞技术是治疗颌骨中心性血管瘤的一种行之有效的方法。
In this paper, 6 cases of central hemangiomas of the jaw treated with digital subtraction angiography (DSA) were enrolled in this study. Histologically resected tissue was treated with this technique. The results showed that after interventional treatment, blood clots in the cavities of the hemangiomas, occlusion of part of the cavities, degeneration and necrosis of the vascular endothelial cells (mainly coagulative necrosis) occurred. Local fibrous connective tissue hyperplasia, the formation of blood clots, and a clear inflammatory response. Electron microscopy: After interventional treatment, the nuclei of the vascular endothelial cells showed nuclear pyknosis, cytoplasmic edema, vacuolar degeneration and mitochondria edema, and the cells lost normal connective structures with widened gaps between the cells. It is proved that digital subtraction angiography (DSA) interventional embolization is an effective method to treat central hemangiomas of the jaw.