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乙胺嘧啶对恶性疟及间日疟的红细胞前型有效,用于疟疾的预防,效果较佳。为目前主要的抗疟药之一。现将我们所见误服乙胺嘧啶过量中毒二例报告如下: 例一,徐××,女,3岁。因当天中午误服乙胺嘧啶6.25毫克×26片(162.5毫克)后约3小时,于1972年9月11日入院。体检:昏迷,两眼直视,口吐白沫,喉头痰鸣,牙关紧闭,青紫,四肢呈阵挛性抽搐,阵发性呼吸肌痉挛引
Pyrimethamine is effective against pre-erythrocytic type of falciparum malaria and Plasmodium vivax, and is used for the prevention of malaria with better effect. As one of the major anti-malaria drugs at present. Now we see the error of taking pyrimethamine overdose poisoning two cases are reported as follows: Example One, Xu × ×, female, 3 years old. Due to the day noon mistaken dose of pyrimethamine 6.25 mg × 26 tablets (162.5 mg) about 3 hours after admission on September 11, 1972. Physical examination: coma, eyes look straight, foaming at the mouth, throat phlegm, teeth closed, bruising, clonic convulsions limbs, paroxysmal respiratory muscle spasm cited