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氧氟沙星(ofloxacin)常见的不良反应为恶心、呕吐、腹泻等,发生率为3.03%,而致过敏性休克极为罕见.【病例】患者女,66a,因慢性咳嗽、咯痰20a,加重7d于1997年8月28日入院,入院查体:BP14/10kPa(100/70 mmHg),意识清楚,慢性病容,口唇无紫绀,桶状胸,双肺呼吸音粗糙,可闻及少许湿啰音,HR 80 beats/min.律齐,无杂音,既往无高血压、心脏病史,无过敏史.入院后根据病史、体征及胸片检查,临床诊断:慢性支气管炎、阻塞性肺气肿.入院后即予iv gtt氧氟沙星葡萄糖注射液(江西鹿迪制药有限公司,批号961218).约15 min后患者出现烦躁不安、表情痛苦、大汗淋漓、胸闷、呼吸困难、口唇紫绀、心跳加快、BP下降(10/6 kPa),随即出现神志不清、大小便失禁,即予停药使其平卧,给氧,im肾上
Ofloxacin (ofloxacin) common adverse reactions of nausea, vomiting, diarrhea, etc., the incidence was 3.03%, and caused by anaphylactic shock is extremely rare. [Case] female patients, 66a, due to chronic cough, expectoration 20a, increased 7d was admitted to hospital on August 28, 1997 and was admitted to the hospital for examination: BP14 / 10kPa (100/70 mmHg). Consciousness, chronic illness, cyanosis-free lips, barrel-shaped chest, rough breathing sounds in both lungs, Sound, HR 80 beats / min. Law Qi, no noise, no previous history of hypertension, heart history, no history of allergy. Admission based on medical history, signs and chest X-ray examination, clinical diagnosis: chronic bronchitis, obstructive emphysema. After admission to iv gtt ofloxacin glucose injection (Jiangxi Ludi Pharmaceutical Co., batch number 961218.) About 15 minutes after the patient irritability, facial pain, sweating, chest tightness, difficulty breathing, lips cyanosis, heart rate Speed up, BP decreased (10/6 kPa), followed by unconsciousness, incontinence, that is to stop taking to supine, oxygen, im kidney