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1-环丙甲基-4-苯基6-氯-2(1H)-喹唑酮(SL-512)是一种较安全的具有强力镇痛和退热作用的新抗炎剂。急性炎症模型试验为:角叉菜胶(Carrageenin)诱发水肿,trafuril诱发的红斑,芥子粉引起的腹膜炎和乙酸引起的染料泄漏等。结果表明,其抗炎效果比甲灭酸(Mefenamic acid)或炎痛静(Benzydamin)强2～4倍,而与保泰松相仿;它还具有与保泰松或甲灭酸强度相似的镇痛和退热作用;对辅料引起的关节炎也有相当效果,但不能阻止肉芽肿的生成。其急性毒性和肠穿孔作用远比其他抗炎药为弱。
Cyclopropylmethyl-4-phenyl 6-chloro-2 (1H) -quinazolone (SL-512) is a safer new anti-inflammatory agent with potent analgesic and antipyretic properties. Acute inflammation model tests were carrageenin-induced edema, trafuril-induced erythema, peritonitis caused by mustard powder, and acetic acid-induced dye leakage. The results showed that the anti-inflammatory effect is 2 to 4 times stronger than Mefenamic acid or Benzydamin and similar to phenylbutazone; it also has a town of similar strength to phenylbutazone or mefenamic acid Pain and fever; arthritis caused by excipients also have a considerable effect, but can not stop the formation of granulomas. Its acute toxicity and intestinal perforation is far weaker than other anti-inflammatory drugs.