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目的观察复方丹参滴丸联合单硝酸异山梨酯注射液治疗冠状动脉粥样硬化性心脏病不稳定心绞痛临床疗效及对心功能的影响。方法选择我科住院诊治的冠心病不稳定性心绞痛的患者112例,随机分为2组,治疗组给予复方丹参滴丸与单硝酸异山梨酯注射液治疗,对照组予单硝酸异山梨酯注射液治疗。两组患者疗程4周。观察两组患者临床疗效及对心功能的影响。结果两组在血压心率方面无差异,在心绞痛发作次数,心功能,心肌缺血恢复程度差异有统计学意义(P<0.05),两药合用的临床疗效均优于对照组。结论复方丹参滴丸可改善心绞痛患者血流变性,增加心肌血供,减慢心率,降低心肌氧耗,以稳定心绞痛。复方丹参滴丸联合单硝酸异山梨酯注射液治疗不稳定心绞痛疗效较好。
Objective To observe the clinical efficacy of compound Danshen dripping pills and isosorbide mononitrate injection in treating unstable angina pectoris of coronary atherosclerotic heart disease and its influence on cardiac function. Methods A total of 112 patients with coronary heart disease and unstable angina pectoris were selected and randomly divided into two groups. The treatment group was treated with compound Danshen dripping pills and isosorbide dinitrate injection, while the control group was given isosorbide mononitrate injection Liquid treatment. Two groups of patients for 4 weeks. The clinical efficacy and cardiac function of the two groups were observed. Results There was no difference in blood pressure and heart rate between the two groups. There were significant differences in the number of angina attacks, cardiac function and myocardial ischemia (P <0.05). The clinical efficacy of the two drugs in combination was better than that of the control group. Conclusion Compound Danshen Dripping Pills can improve blood rheology of patients with angina pectoris, increase blood supply of cardiac muscle, slow down heart rate, reduce myocardial oxygen consumption and stabilize angina pectoris. Compound Danshen dripping pills with isosorbide mononitrate injection for the treatment of unstable angina better effect.