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中药治疗肾炎已获得一定临床疗效,对黄芪的作用,说法不一。本文为此复制了家兔Masugi肾炎模型,并就黄芪对家兔实验性抗肾抗体肾炎的疗效及作用机理进行初步探讨。主要结果摘要如下: 一、黄芪对实验性抗肾抗体肾炎家兔的食欲、体重的增长及一般状况等均有良好作用。可能与一般强壮作用有关。黄芪还可加速虚证明显病兔的尿蛋白消退及肾小球荧光的消失,相反,黄芪对虚证不明显者作用较差,尿蛋白的消退及肾小球荧光的消失均较对照组稍慢,这可能是黄芪加重了病变
Traditional Chinese medicine has been used to treat nephritis and has achieved certain clinical efficacy. There are different opinions on the effects of jaundice. In this paper, a rabbit Masugi nephritis model was reproduced, and the efficacy and mechanism of experimental anti-kidney antibody nephritis in rabbits were initially discussed. The main results are summarized as follows: 1. Astragalus has a good effect on the appetite, weight gain and general condition of rabbits with experimental anti-kidney antibody nephritis. May be related to the general strong effect. Astragalus can also accelerate the deficiency of urinary protein excretion and glomerular fluorescence in deficiency-proven rabbits. On the contrary, Astragalus membranaceus has poorer effects on deficient patients, and the disappearance of urine protein and disappearance of glomerular fluorescence are slightly lower than those in the control group. Slow, this may be aggravating the lesions