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采用A型肉毒毒素局部多点肌肉注射治疗偏侧面肌痉挛30例,治疗后随访时间5~14个月。用Shorr量表对治疗前后面肌痉挛的程度进行评估。结果显示:一次注射后痉挛变为0级20例(67%),见效时间平均4,2天,疗效维持时间平均18.6周。11例出现局部轻微的副作用:上睑下垂(3例)、闭目不全(4例)、口角下垂(4例),3个月内自行消失。10例因有部分复发,于1~2个月重复注射,同样于2~7天内取得疗效。
A type botulinum toxin local multi-point intramuscular injection of hemifacial spasm in 30 cases, after treatment, follow-up time of 5 to 14 months. The degree of hemifacial spasm before and after treatment was evaluated by Shorr scale. The results showed that after one injection, spasticity became grade 0 in 20 cases (67%), the effective time was 4 and 2 days on average, and the curative effect was maintained for an average of 18.6 weeks. Eleven patients had local minor side effects: ptosis (3 cases), closed eyes (4 cases), mouth drooping (4 cases) and disappeared within 3 months. 10 cases due to some relapse, repeated injection in 1 to 2 months, the same effect in 2 to 7 days.