小涎腺癌最多见于口腔,这是因为在口腔内存在着450～750个小腺体,多数腺体位于硬腭粘膜下,通过较短的导管向口腔分泌液体。除口腔外,鼻腔、副鼻窦、鼻咽、口咽和喉也有小涎腺存在。小涎腺肿瘤中,82％为恶性,而相比之下,腮腺和颌下腺的恶性肿瘤分别占15％和50％。小涎腺癌约占所有口腔癌的10％,占全部涎腺癌的15％～23％,其临床表现、组织学类型和行为之间差别很大。作者回顾过去35年间收治的95例小涎腺癌病例,旨在确定临床与组织学因素对患者预后的影响。 复习95例患者的病历资料与组织切片,年龄8～87岁(中位年龄55岁),部位以口腔居多(64例),其次为硬腭。病理学上以腺样囊性癌最多(43％),初诊时颈 Small salivary gland carcinoma is found mostly in the mouth, because there are 450 to 750 small glands in the mouth, most of the glands are located under the hard palate mucosa and fluid is secreted into the oral cavity through shorter catheters. In addition to the oral cavity, the nasal cavity, paranasal sinuses, nasopharynx, oropharynx and larynx also have small salivary glands. In salivary gland tumors, 82% is malignant, compared with 15% and 50% for parotid and submandibular gland malignancies, respectively. Small salivary gland cancer accounts for about 10% of all oral carcinomas, accounting for 15% ~ 23% of all salivary gland cancers, and its clinical manifestations, histological types and behaviors vary greatly. The authors reviewed 95 cases of small salivary gland cancer that had been treated in the past 35 years to determine the impact of clinical and histologic factors on the prognosis of patients. The medical records and histological sections of 95 patients were reviewed. Their ages ranged from 8 to 87 years (median age 55 years). The majority of the patients were oral cavity (64 cases), followed by hard palate. Pathologically, the most adenoid cystic carcinoma (43%), the first diagnosis of neck