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碘化造影剂胺碘苯丙酸钠(sodium ipodate)可抑制甲状腺素(T_4)向三碘甲腺原氨酸(T_3)转换。本文通过对18例 Graves 病(男15,女3)的观察,试图确定在常规心得安和丙基硫氧嘧啶(PTU)治疗的基础上加用胺碘苯丙酸钠能否显著降低循环中 T_4水平。患者服心得安将休息时脉率控制在80～90次/min,并每8h 日服 PTU100mg。病情稳定后,观察组10例男性每日加用胺碘苯丙酸钠1g 6～13日(平均9.1±0.9日),加药前基础治疗期平均为2.7±0.3
The iodinated contrast agent sodium ipodate inhibits the conversion of thyroxine (T_4) to triiodothyronine (T_3). In this paper, 18 patients with Graves’ disease (male 15, female 3) were examined to determine whether adding amiodarone reduced the circulation significantly on the basis of conventional propranolol and propylthiouracil (PTU) treatment T_4 level. Patient service peacetime rest pulse rate control in 80 to 90 times / min, and PTU every 8h 100mg. Condition was stable, the observation group of 10 men daily with amiodarone sodium 1g 6 to 13 days (mean 9.1 ± 0.9 days), before treatment, the average treatment period was 2.7 ± 0.3