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目的探讨甲型H1N1流感病毒抗体血浆用于危重甲流患者的治疗效果。方法采集制备H1N1抗体血浆,选择甲型H1N1流感病毒核酸检测阳性、经省专家组会诊判断为危重的患者,结合患者病情静脉输入200ml抗体血浆,观察其病程变化及治愈情况。结果4名危重甲流患者经抗体血浆联合抗病毒治疗后治愈3例,死亡1例。讨论抗体血浆治疗甲流危重患者有一定的治疗效果,适合于流行病区治疗,但还需进一步模索使用方法。
Objective To investigate the therapeutic effect of the antibody against type A H1N1 influenza virus in patients with critical A-flow. Methods The plasma of H1N1 antibody was collected and the positive samples were selected for the detection of influenza A (H1N1) virus. The patients diagnosed as critically ill by the provincial expert group were treated with intravenous injection of 200 ml of antibody plasma in order to observe the course of disease and cure. Results In 4 patients with critical A-flow disease, 3 cases were cured by antibody-plasma combined with antiviral therapy and 1 died. Discuss the antibody plasma treatment of patients with a serious risk of treatment have a certain effect, suitable for treatment of epidemic disease, but still need to further explore the use of methods.