论文部分内容阅读
目的:分析卵巢交界性肿瘤(BOT)患者术中冰冻切片检查及大网膜种植率在交界性肿瘤诊断及治疗中的价值,并进一步分析保留生育功能手术患者术后月经恢复情况及妊娠结局。方法:收集2007年1月至2014年12月在山东大学齐鲁医院妇科住院的92例卵巢交界性肿瘤患者的临床特点及治疗情况,随访保留生育功能患者的月经恢复及妊娠情况,并进行统计分析。结果:病理类型是影响冰冻切片与石蜡切片诊断符合率的主要影响因素,交界性浆液性肿瘤(SBOT)与黏液性交界性肿瘤肿瘤(MBOT)相比,符合率高(94.5%vs 80.0%),差异有统计学意义(P=0.043)。卵巢包膜表面种植是大网膜种植的相关因素(P=0.002)。腹腔镜与经腹保留生育功能手术相比,术后妊娠率、足月产率、术后妊娠间隔时间、术后月经复潮时间比较均无统计学差异(P>0.05)。结论:MBOT术中冰冻切片检查与常规病理检查符合率较低,病理医生及手术医生需提高警惕。大网膜种植多见于IIB期以上的患者,对于I期患者可适当保留目检正常的大网膜。
Objective: To analyze the value of intraoperative frozen section examination and omentum implantation rate in the diagnosis and treatment of borderline tumors in patients with borderline ovarian tumor (BOT), and further analyze the postoperative menstruation recovery and pregnancy outcome in patients with reproductive function. Methods: The clinical features and treatment of 92 patients with ovarian borderline tumor who were hospitalized in Gynecology Department of Qilu Hospital of Shandong University from January 2007 to December 2014 were collected. Menstruation recovery and pregnancy of patients with reproductive function were followed up and analyzed statistically . Results: The pathological type was the main influencing factor for the coincidence rate of frozen sections and paraffin sections. The borderline serous tumors (SBOT) had a higher coincidence rate (94.5% vs 80.0%) than the mucinous borderline tumors (MBOT) , The difference was statistically significant (P = 0.043). Survival of the ovarian capsule surface is a correlate of omentum implantation (P = 0.002). There was no significant difference in postoperative pregnancy rate, full-term birth rate, postoperative pregnancy interval and postoperative menstrual resuscitation time between laparoscopic surgery and transabdominal retained fertility surgery (P> 0.05). Conclusion: There is a low coincidence rate between frozen section examination and routine pathological examination in MBOT, and vigilance should be paid to pathologists and surgeons. Omental planting more common in patients with stage IIB more than for patients with stage I may properly retain the normal visual inspection of the omental.