摘要目的评价增强CT检查是否会造成慢性肾疾病病人肾损伤分子-1(KIM-1)和中性粒细胞明胶酶相关脂质运载蛋白(N-GAL)的分泌量增加。材料与方法病人来自一项使用水化法防止增强后导致的急性肾损伤(CI-AKI)的试验。病人的血液及尿液样本分别于增强CT扫描前、扫描后4~6 h及48~96 h采集。KIM-1和N-GAL被换算成尿肌酸酐水平,测量数据结果用中位数表示。结果在所有511例入组 Abstract Objective To evaluate whether enhanced CT examination can cause an increase in the secretion of renal injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (N-GAL) in patients with chronic kidney disease. MATERIALS AND METHODS Patients were from a trial using hydration to prevent enhanced acute kidney injury (CI-AKI). Patient’s blood and urine samples were collected at 4 ~ 6 h and 48 ~ 96 h after CT scan enhancement. KIM-1 and N-GAL were converted to creatinine levels in urine and measured data were presented as median. The result was enrolled in all 511 cases