五味子醇甲类似物9是五味子醇甲的代谢产物之一。本文以没食子酸为原料,经甲基化,Henry缩合、还原和分子间还原偶合等六步反应得到了具有苏、赤式两种构型的中间体7,再经DDQ作试剂的非酚氧化偶合反应完成了化合物9的全合成。同时得到另一新化合物10,并对两种产物的生成机制作了探讨。药理结果表明:化合物9具有与五味子醇甲相当的抗惊活性. Schisandrin A analog 9 is one of the metabolites of Schisandra. In this paper, gallic acid as raw material, methylation, Henry condensation, reduction and intermolecular reduction coupling six-step reaction with the Soviet Union, the red two configurations of the intermediate 7, and then DDQ as a reagent for non-phenol oxidation The coupling reaction completes the total synthesis of compound 9. At the same time, another new compound 10 was obtained, and the formation mechanism of the two products was discussed. Pharmacological results show that: Compound 9 has a comparable anti-shock Schizandrin A activity.