Based on the information fusion theory, a kind of integrated navigation system integration for cruise missile is presented in this paper. Besides, the way with which the system is integrated and the related data fusion technique are discussed. Information-fusion-based hybrid navigation system integration can fully utilize information provided by all kinds of navigation sensor subsystem and can improve the precision of the system effectively. Simultaneously, the reconstructing ability ensures the system of great reliability. Based on the information fusion theory, a kind of integrated navigation system integration for cruise missile is presented in this paper. Information fusion-based hybrid navigation system integration can fully utilize information provided by all kinds of navigation sensor subsystem and can improve the precision of the system effectively. Simultaneously, the reconstructing ability ensures the system of great reliability.