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目的探讨三氯乙烯以及四氯乙烯室内空气污染与不良分娩结局的关系。方法选取深圳市坪山新区2008-12/2013-05接诊的暴露于三氯乙烯以及四氯乙烯室内空气污染的孕妇132例为观察组,根据分娩季节分为2组,在非采暖期分娩的孕妇94例为观察A组,在采暖期分娩的孕妇38例为观察B组,选取深圳市坪山新区同期接诊的未暴露于三氯乙烯以及四氯乙烯室内空气污染的孕妇128例为对照组,分析各组孕妇的分娩情况及胎儿情况。结果观察组胎儿体重、孕周均明显小于对照组,观察组早产儿发生率、低体重发生率均高于对照组,差异均有统计学意义(P<0.05)。观察组顺产率低于对照组,观察组心脏缺陷发生率、死胎发生率均高于对照组,观察B组顺产率明显低于观察A组,观察B组胎儿体重、孕周均小于观察A组,观察B组早产儿发生率、低体重发生率、心脏缺陷发生率、死胎发生率均高于观察A组,但差异均无统计学意义(P>0.05)。结论三氯乙烯以及四氯乙烯室内空气污染可造成不良分娩结局的发生,与季节无关。
Objective To explore the relationship between indoor air pollution of trichlorethylene and tetrachlorethylene and the outcome of poor delivery. Methods A total of 132 pregnant women exposed to trichlorethylene and PCE in the Pingshan New District of Shenzhen City from December 2008 to May 2013 were selected as the observation group and divided into two groups according to the delivery season and delivered during the non-heating period A total of 94 pregnant women were enrolled in group A, 38 pregnant women giving birth in heating period were observed in group B, 128 pregnant women who were not exposed to trichlorethylene and PCE in the same period in Pingshan New District, Shenzhen were selected as control group , Analysis of each group of pregnant women, childbirth and fetal conditions. Results The body weight and gestational age of the observation group were significantly less than those of the control group. The incidence of preterm birth and the incidence of low body weight in the observation group were significantly higher than those in the control group (P <0.05). The birth rate in observation group was lower than that in control group. The incidence of heart defects and stillbirth in observation group were higher than those in control group. The birth rate in observation group B was significantly lower than that in observation group A. The body weight and gestational age in group B were less than those in observation group A The incidence of premature infants, the incidence of low weight, the incidence of heart defects and the incidence of stillbirth in group B were higher than those in group A (P> 0.05). Conclusion Trichlorethylene and PCE indoor air pollution can cause adverse childbirth outcomes, regardless of season.