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目的：探讨几种肝病患者外周血可溶性白细胞介素２受体（ｓＩＬ２Ｒ）水平状态及其临床意义。方法：采用双抗体夹心ＥＬＩＳＡ法检测慢性乙型肝炎、肝硬化和原发性肝癌患者（共７０例）与健康人（２２例）的外周血ｓＩＬ２Ｒ水平，并比较原发性肝癌（１５例）手术前后ｓＩＬ２Ｒ水平的变化。结果：与对照组相比，慢性乙型肝炎、肝硬化和原发性肝癌患者的ｓＩＬ２Ｒ水平明显增高；肝癌术后ｓＩＬ２Ｒ水平明显下降；ｓＩＬ２Ｒ水平与肝癌临床分期相关。结论：进一步证实血清ｓＩＬ２Ｒ水平可间接反映几种肝病的细胞免疫功能状态。
Objective: To investigate the serum levels of soluble interleukin 2 receptor (sIL 2R) in peripheral blood and its clinical significance in several liver diseases. Methods: The levels of sIL2R in peripheral blood of patients with chronic hepatitis B, cirrhosis and primary liver cancer (70 cases) and healthy people (22 cases) were detected by double antibody sandwich ELISA. Cases) before and after surgery sIL 2R level changes. Results: Compared with the control group, the levels of sIL2R in patients with chronic hepatitis B, cirrhosis and primary liver cancer were significantly increased; the levels of sIL2R in patients with liver cancer were significantly decreased; and the levels of sIL2R were correlated with the clinical stage of liver cancer. Conclusion: It is further confirmed that serum sIL 2R levels can indirectly reflect the cellular immune function of several liver diseases.