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醋酸甲地孕酮(美可治,ＭＡ)已广泛用于转移性乳癌的治疗。ＭＡ的副作用除体重增加、血栓栓塞、月经崩漏、高血压等,新近有人报道久服ＭＡ可致肾上腺功能不全(ＡＩ)。本文作者近来亦观察到类似现象,并就此作了进一步研究。病例和方法 1988～1993年住院者中,转移性乳癌妇女39例,
Megestrol acetate (Meike, MA) has been widely used in the treatment of metastatic breast cancer. Side effects of MA in addition to weight gain, thromboembolism, menstrual metrorrhagia, high blood pressure, recently it was reported that long service MA can cause adrenal insufficiency (AI). The authors of this article have also observed similar phenomena lately, and have made further research on this point. Cases and methods 1988 to 1993 inpatients, 39 cases of metastatic breast cancer women,