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妊娠8～18周、胎囊≥3.0cm的妇女100例,随机分为实验和对照两组,每组50例,进行药物终止妊娠临床效果的比较性研究。实验组应用米非司酮合并丙酸睾丸酮配伍PG05;对照组单用丙酸睾丸酮配伍PG05。两组效果间比效,实验组和对照组的完全流产率各为96％和84％(P<0.05);宫内物6小时内排出率为85.4％和45.2(P<0.0001);药物副反应发生率为76％和96％(P<0.01),反应程度实验组比对照组明显减轻;PG05用量为1.3±0.75粒和3.5±1.30粒(P<0.001),以上均有显著性差别。提示米非司酮合用后能显著提高丙酸睾丸酮配伍PG05的临床效果,为终止大于49天的妊娠提供了药物流产新方法。
Pregnancy 8 to 18 weeks, fetal capsule ≥ 3.0cm of 100 women were randomly divided into experimental and control groups, 50 cases in each group, the clinical effect of drug termination pregnancy comparative study. The experimental group used mifepristone combined with testosterone propionate PG05; control group testosterone propionate PG05 alone. The two groups of the effect of the specific effect, the experimental group and the control group, the complete abortion rate was 96% and 84% (P <0.05); intrauterine intrauterine discharge within 6 hours 85.4% and 45.2 (P <0.0001); drug The reaction rates were 76% and 96% respectively (P <0.01), and the degree of reaction was significantly reduced in the experimental group compared with the control group. The PG05 dosage was 1.3 ± 0.75 and 3.5 ± 1.30, respectively (P <0.001). Tip mifepristone combined can significantly improve the clinical efficacy of testosterone propionate with PG05, termination of more than 49 days of pregnancy provides a new method of medical abortion.