为了解新生儿经口气管插管机械通气合并医院内下呼吸道感染情况，在４７例经口气管插管机械通气中随机抽取３３例患儿，收集４２份气管分泌物进行培养，结果细菌和真菌的感染率达５９．５％，铜绿脓杆菌占４８％。气管插管机械通气持续时间意长．感染率愈高，超过７天达１００％。药敏结果丁胺卡那霉素、氟哌酸和头孢塞甲羧肟敏感．其他抗生素敏感性较差。因此提出了预防该病的重要性及其具体措施。 In order to understand the neonatal bronchial intubation mechanical ventilation combined with lower respiratory tract infection in hospitals, 33 cases of children were randomly selected from 47 cases of mechanical ventilation through orotracheal intubation, 42 tracheal secretions were collected for culture, the results of bacteria and fungi The infection rate was 59.5%, Pseudomonas aeruginosa accounted for 48%. Endotracheal intubation duration of mechanical ventilation intended. The higher the infection rate, more than 7 days up to 100%. Susceptibility results of amikacin, norfloxacin and cefotetone oxime are sensitive. Other antibiotics are less sensitive. Therefore, the importance of preventing this disease and its specific measures are put forward.