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目的:观察用卡维地洛治疗慢性心力衰竭的临床疗效。方法:将我院2010年2月～2011年2月收治的92例慢性心力衰竭的患者随机分成两组,其中一组为对照组(46例),对照组患者进行强心、利尿、扩血管等常规治疗,另外一组为观察组(46例),观察组患者在对照组治疗的基础上加用卡维地洛进行治疗。连续治疗10周后,比较两组患者的治疗效果。结果:①观察组患者治疗的总有效率(91.3%)高于对照组患者治疗的总有效率(73.9%),且两组间的差异具有显著性(p<0.05);②观察组患者的心率、收缩压、舒张压、左室舒张末径这四项指标均低于对照组患者;③观察组患者的左室射血分数高于对照组患者的左室射血分数;④观察组患者出现的不良反应轻而少,主要表现有低血压和头晕(后经治疗均得到改善)。结论:用卡维地洛治疗慢性心力衰竭具有疗效显著、安全性高等特点,是一种值得在临床上推广和应用的治疗慢性心力衰竭的药物。
Objective: To observe the clinical efficacy of carvedilol in the treatment of chronic heart failure. Methods: A total of 92 patients with chronic heart failure who were admitted to our hospital from February 2010 to February 2011 were randomly divided into two groups, one of which was the control group (46 cases). The patients in the control group were given cardiac, diuretic and vasodilator And other conventional treatment, the other one for the observation group (46 cases), the observation group patients in the control group based on the treatment with carvedilol for treatment. After 10 weeks of continuous treatment, the treatment effect was compared between the two groups. Results: ① The total effective rate (91.3%) in the observation group was higher than that in the control group (73.9%), and the difference between the two groups was significant (p <0.05); ② The total effective rate Heart rate, systolic blood pressure, diastolic blood pressure, left ventricular diastolic diameter of the four indicators were lower than the control group patients; ③ observation group patients with left ventricular ejection fraction higher than the control group patients with left ventricular ejection fraction; ④ observation group patients Adverse reactions were mild and few, the main manifestations of hypotension and dizziness (after treatment have been improved). Conclusion: The treatment of chronic heart failure with carvedilol has obvious curative effect and high safety. It is a kind of medicine which is worth popularizing and applied in clinical treatment of chronic heart failure.