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鼻腔及其相邻部分,如咽、腭部原发的进行性坏疽性病变,进展时累及周围组织,并可表现出全身各器官的变化。自1896年Mc Bride报告本病以来,不少作者相继发表了较多临床研究资料。但迄今为止,诊治本病仍较困难。有关本病的名称繁杂而混乱,如:坏疽性肉芽肿、恶性肉芽肿、致死性中线肉芽肿、特发性坏疽性鼻炎、鼻网织肉瘤等。近年来,有人主张将本病分为两大类:(1)Wegener氏肉芽肿(W.G.):属于自身免疫性疾病;(2)网织肉瘤:属于肿瘤性疾病。但在实际上,常难于区别这两种类型,且有过渡形态存在,因而不清楚的问题尚多。作者将其统称为进行性鼻坏疽,总结1957～1972年共16年间经治的15例本病患者的经验,并复习文献,对本病进行了临床方面的研究。有关本病的本质问题等资料
Nasal cavity and its adjacent parts, such as pharynx, palatal primary progressive gangrenous lesions involving the surrounding tissue progress, and can show changes in all body organs. Since 1896, McBride reported the disease, many authors have published more clinical research data. But up to now, it is still more difficult to diagnose and treat this disease. The name of the disease complicated and confusing, such as: gangrenous granuloma, malignant granuloma, lethal median granuloma, idiopathic gangrenous rhinitis, rhinosarcoma sarcoma and so on. In recent years, some people advocate the disease is divided into two categories: (1) Wegener’s granulomatosis (W.G.): belong to autoimmune diseases; (2) reticulosarcoma: a neoplastic disease. However, in practice, it is often difficult to distinguish between the two types and there are transitional forms, so there are still many problems that are unclear. The authors collectively referred to as progressive gangrene, summarize the experience of 15 patients with this disease in 1957 to 1972, and reviewed the literature, the clinical aspects of the disease. The nature of the disease and other information