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日本学者Kodama[1]和Oitwa[2]研究表明，早期胃癌由于生长方式不同，术后生存时间也有明显差异。P53表达与肿瘤生长方式有一定相关性。本研究采用免疫组化染色，探讨P53表达与早期胃癌生长方式及预后的关系。1资料与方法1.1临床标本胃癌标本来自河南省肿瘤医院病理科手术石蜡切
Studies by Japanese scholars Kodama [1] and Oitwa [2] have shown that early gastric cancer has significant differences in survival time due to different growth patterns. There is a certain correlation between P53 expression and tumor growth pattern. In this study, immunohistochemical staining was used to investigate the relationship between P53 expression and the growth pattern and prognosis of early gastric cancer. 1 Materials and Methods 1.1 Clinical specimens of gastric cancer specimens from the Department of Pathology, Henan Provincial Cancer Hospital, surgical paraffin incision