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放射受体鉴定法是测定生物液中激素水平的一种敏感性很高的最新方法,它根据激素和靶子组织上的受体具有亲和性和特异性结合的原理,用放射性同位素标记的激素,和欲测定的体液中的激素,使其与靶子组织上的受体作竞争性结合,从而测定体液中该激素的含量。一般来讲,欲测定的体液中激素含量越多,含放射性的受体的量就越少,反之亦然。也就是说,放射性受体的量与体液中激素的量呈一定的函数关系。放射受体鉴定法已被用来测定人血液中绒毛膜促性腺激素(HCG)或促黄体生成素(LH),其灵敏度大于3毫微克/毫升,最小的可测值在70微微克左右,并与其它激素不发生交叉反应。因此,用放射受体鉴定法在怀孕的第6～8天就可测到血浆中的HCG水平的升高,这要比用目前较新的放射免疫法(在妊娠的第9天时才能测得HCG)
Radiation receptor identification is a highly sensitive and recent method for determining hormone levels in biological fluids based on the principle of affinity and specific binding of receptors on hormones to target tissues. Radiological isotope labeled hormones , And the hormone in the body fluid to be assayed to compete with the receptor on the target tissue to determine the level of the hormone in the body fluid. In general, the more hormone content in a body fluid to be measured, the less the amount of radioactive acceptor, and vice versa. In other words, the amount of radioactive receptors and body fluids in a certain amount of hormones as a function of the relationship. Radioligand identification has been used to determine human chorionic gonadotropin (HCG) or luteinizing hormone (LH) with a sensitivity greater than 3 ng / ml and a minimum detectable value of about 70 pg, And does not cross-react with other hormones. Therefore, radioimmunoassay can detect an increase in plasma HCG levels on days 6-8 of pregnancy, as measured by the more recent radioimmunoassay (measured on day 9 of pregnancy HCG)