既往研究发现,瘦素与代谢综合征罹患风险增加明显相关,并可影响纤溶、血管功能及炎性指标,既而认为循环内瘦素增加将增高罹患冠心病(CHD)风险,亦认为为其独立风险因素之一。但关于上述观点尚需大样本研究加以证实。本文意就循环内瘦索水平与CHD罹患风险间关系进行了大样本调查分析。 Previous studies have found that leptin is significantly associated with an increased risk of developing metabolic syndrome and can affect fibrinolysis, vascular function, and inflammatory markers, suggesting that an increased circulating leptin will increase the risk of coronary heart disease (CHD) and is considered as One of the independent risk factors. However, this view still needs to be confirmed by a large sample of studies. This article intended to investigate the relationship between the level of circulating leptin and the risk of CHD conducted a large sample survey.