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目的比较淫羊藿生、炙品及纳入复方的抗炎、镇痛活性,为淫羊藿生熟异用提供依据。方法采用热板法考察镇痛作用,运用二甲苯致耳肿胀实验评价抗炎活性。结果与正常组比,生、炙品高剂量均具显著抗炎作用(P<0.05),复方生品高剂量具显著抗炎作用(P<0.05);生品高剂量具显著的镇痛作用(P<0.05),复方生品中剂量具显著镇痛作用(P<0.05)、高剂量具极显著镇痛作用(P<0.01)。结论淫羊藿生、炙品皆具抗炎镇痛作用,且生品强于炙品。
OBJECTIVE To compare the anti-inflammatory and analgesic activity of Epimedium brevicornum, Sunburn products and the compound prescription, and to provide basis for epimedium breed. Methods The analgesic effect was investigated by hot plate method. The anti-inflammatory activity was evaluated by xylene-induced ear swelling test. Results Compared with normal group, the high dose of raw and sunburn products had significant anti-inflammatory effect (P <0.05), high dose of compound prescription had significant anti-inflammatory effect (P <0.05); high dose of raw product had significant analgesic effect (P <0.05). The medium dose of compound prescription had significant analgesic effect (P <0.05), and the high dosage had very significant analgesic effect (P <0.01). Conclusion Epimedium, Sunburn products have anti-inflammatory and analgesic effects, and raw products stronger than the Sunburn products.