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近年来国内外对β_2微球蛋白(β_2-m)的生物学特性和临床应用作了较详细的研究,但对血吸虫病患者临床诊断的意义研究较少。我们在1991年4月—1993年2月用放射免疫(RIA)方法,测定146例不同类型血吸虫病患者血清β_2-m含量,同时测定血清尿素氮(BUN)、肌酐(Cr)作对比观察,并对晚期血吸虫病(下称晚血)患者β_2-m含量增高的病理机制及临床意义作了初步探讨。
In recent years, the biological characteristics and clinical application of β_2 microglobulin (β_2-m) have been studied in detail at home and abroad, but there are few researches on the clinical diagnosis of schistosomiasis. We measured the serum levels of β_2-m in 146 patients with different types of schistosomiasis by radioimmunoassay (RIA) from April 1991 to February 1993, and measured the levels of serum urea nitrogen (BUN) and creatinine (Cr) The pathological mechanism and clinical significance of β 2-m in patients with advanced schistosomiasis (hereinafter referred to as late blood) were also discussed.