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目的 探讨治疗 2型糖尿病周围神经病变有效方法 ,改善病人生活质量。方法 选择 2型糖尿病并伴有不同程度周围神经病变临床症状患者 82例 ,随机分为两组。在常规应用口服降糖药物或胰岛素的治疗基础上 ,观察组加用弥可保 5 0 0 μg、6 5 4 2 10mg ,各加入生理盐水 2 5 0mL中静脉滴注 ,每日 1次 ;对照组加用复方丹参注射液 2 0mL加入生理盐水 2 5 0mL中静脉滴注 ,每日 1次。疗程均为 4周。结果 观察组总有效率 81% ,部分病人尺神经、胫神经和腓总神经传导速度恢复正常 ,与对照组比较差异均有显著性 (P <0 0 5 )。结论 弥可保与 6 5 4 2合用治疗糖尿病周围神经病变是一种有效的方法。
Objective To explore effective methods for the treatment of type 2 diabetic peripheral neuropathy to improve the quality of life of patients. Methods 82 patients with type 2 diabetes mellitus and clinical symptoms of peripheral neuropathy were randomly divided into two groups. In the conventional application of oral antidiabetic drugs or insulin treatment based on the observation group plus Mi Kebao 500 g, 6 5 4 2 10mg, each added 250 mL of normal saline intravenously once daily; control Group plus compound Danshen injection 20mL normal saline 250mL intravenous infusion, once daily. The course of treatment is 4 weeks. Results The total effective rate was 81% in the observation group. The conduction velocity of the ulnar nerve, tibial nerve and common peroneal nerve in some patients returned to normal, with significant difference compared with the control group (P <0.05). Conclusion Combination of methycobarbine and 6 5 4 2 in the treatment of diabetic peripheral neuropathy is an effective method.