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越来越多的医生们对习惯性流产施行同种基因淋巴细胞免疫治疗。因此迫切地需要明确抗体产生的机理。作者选择了19份被认为具有维持正常妊娠必要抗体阳性或阴性结果的血清,将一位28岁健康无输血史的男性血清作为阴性对照;将补体依赖细胞毒素和免疫吞噬抑制与HLA-A_2阳性细胞呈相同反应的血清作为阳性对照,另一个阳性对照是作静脉内应用的商业性有效的混合人免疫球蛋白G。
More and more doctors apply allogeneic lymphocyte immunotherapy to habitual abortion. Therefore, there is an urgent need to clarify the mechanism of antibody production. The authors selected 19 serums considered to have the positive or negative antibody results necessary to maintain normal pregnancy. A 28-year-old healthy male without blood transfusion was used as a negative control. Complement-dependent cytotoxins and immune phagocytosis were associated with HLA-A 2 -positive Serum cells with the same response were used as a positive control and the other positive control was a commercially available mixed human immunoglobulin G for intravenous use.