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目的:探讨CT平扫测量心外膜及心周脂肪体积与颈动脉粥样硬化斑块的关系。方法:选取开滦集团高管健康查体职工475例,均接受胸部CT平扫检查,测量相应心外膜及心周脂肪体积。根据颈动脉彩超结果将其分为有斑块组165例和无斑块组310例,并进一步以BMI(kg/m2)“24”、“28”分别作为超重、肥胖的界限,将其分为正常体重组129例、超重组258例和肥胖组88例。分别研究正常体重组、超重组和肥胖组中有无颈动脉斑块者的心外膜及心周脂肪体积的相关性。结果:正常体重组有颈动脉斑块者45例,无斑块者84例;超重组有斑块者86例,无斑块者172例;肥胖组有颈动脉斑块者34例,无斑块者54例,3组中有颈动脉斑块的心外膜及心周脂肪体积均大于无颈动脉斑块的,差异有统计学意义(P<0.05)。结论:心外膜及心周脂肪体积随着肥胖程度的增加而增加,排除BMI因素,心外膜及心周脂肪体积与颈动脉粥样硬化斑块形成具有较强的相关性。
Objective: To investigate the relationship between epicardial and peri-fat volume and carotid atherosclerotic plaque measured by CT plain scan. Methods: 475 health workers of Kailuan Group were included in the survey, all underwent plain CT scan and the corresponding epicardial and peri-fat volume was measured. According to the result of carotid ultrasonography, it was divided into plaque group (n = 165) and plaque group (n = 310), and then BMI (kg / m2) , Divided into 129 cases of normal weight group, 258 cases of overweight group and 88 cases of obesity group. The correlation between epicardial and peri-fat volume in carotid atherosclerotic plaque of normal weight group, overweight group and obesity group were studied. Results: There were 45 cases of carotid artery plaque in normal weight group and 84 cases without plaque. There were 86 cases in plaque overweight group and 172 cases without plaque. There were 34 cases of carotid artery plaque in obesity group, In 54 cases, the epicardial and peri-fat volume of carotid artery plaque in 3 groups was larger than that in non-carotid artery plaque, the difference was statistically significant (P <0.05). CONCLUSION: The epicardial and peri-cardiac fat volume increased with the increase of obesity. There was a strong correlation between BMI, epicardial and peri-fat volume and carotid atherosclerosis plaque formation.