J.Am.Chem.Soc.2014,136,12261~12264受阻路易斯酸碱对(FLPs)化学的发展为非金属催化氢化提供了崭新的途径,一系列不饱和化合物的催化氢化反应相继实现,但相应的不催对称催化氢化仍处于起步阶段,反应的对映选择性低于90%,同时底物也仅限于亚胺和喹啉两类化合物.因此发展高对映选择性的不对称催化新体系是这个领域中亟待解决的重要挑战性难题之一.中国 J. Am. Chem. Soc. 2014, 136, 12261-12264 The development of blocked Lewis acid-base (FLPs) chemistry has provided a new avenue for non-metallic catalytic hydrogenation. A series of catalytic hydrogenation reactions of unsaturated compounds have been achieved The corresponding non-catalytic symmetric catalytic hydrogenation is still in its infancy, the reaction enantioselectivity of less than 90%, while the substrate is limited to both imine and quinoline compounds.Therefore, the development of high enantioselectivity catalytic asymmetry The system is one of the most important challenges to be solved in this area