脑水肿是神经科危重患者常见的一种病变,也是脑血管病、颅内占位性病变、颅脑损伤和炎症等过程的主要病理生理改变。近年来,在对脑创伤、脑缺血的细胞分子水平研究中,对引起血脑屏障(BBB)损害和细胞代谢紊乱的原因,有了一些新的发现,从而加深了对脑水肿发生机制的认识。1微循环 Brain edema is a common neurological disease in patients with critically ill, but also the main pathophysiological changes in cerebrovascular disease, intracranial space-occupying lesions, brain injury and inflammation. In recent years, there has been some new discoveries on the causes of blood brain barrier (BBB) ​​damage and cell metabolic disorders in the study of the molecular level of traumatic brain injury and cerebral ischemia, thus deepening the mechanism of brain edema understanding. 1 microcirculation