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目的 :研究内镜下微波加局部注射药物治疗食管贲门癌的临床疗效。方法 :先用微波对肿瘤病灶进行烧灼治疗 ,然后局部注射丝裂霉素 8mg和氟尿嘧啶 0 .2 5 g ,每周治疗 1次 ,连续 6周为 1个疗程。 结果 :经 1个疗程治疗后 ,97% (91/ 94)梗阻症状有了明显的改善 ,98% (92 / 94)食管腔有不同程度扩大。结论 :内镜下微波加局部注射丝裂霉素和氟尿嘧啶治疗中晚期食管贲门癌性梗阻有较好疗效 ,可重建腔道 ,解除梗阻 ,改善临床症状 ,从而起到延长病人寿命的效果。
Objective: To study the clinical efficacy of endoscopic microwave plus local injection in the treatment of esophageal and cardiac cancer. Methods: First, the tumors were treated with microwave cauterization, and then local injection of mitomycin 8mg and fluorouracil 0.52g, once a week for 6 weeks for a course of treatment. Results: After a course of treatment, the symptoms of obstruction in 97% (91/94) were significantly improved, and 98% (92/94) of esophageal cavity were enlarged to some extent. Conclusion: Endoscopic microwave plus local injection of mitomycin and fluorouracil in the treatment of advanced esophageal and gastric cardia obstruction has a good effect, can reconstruct the lumen, relieve the obstruction and improve the clinical symptoms, thus prolonging the life of the patient.