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Ketorolac tromethamine(KT)是美国用于肌注的一种非固醇类抗炎药。本研究旨在比较此药根尖周注射与肌肉注射对牙髓疼痛的止痛效果。 作者选择52例(18～65岁)身体健康的急性牙髓炎患者,每例患者在接受三角肌肌肉注射1ml及邻近痛牙作根尖周注射1.8ml后,作基线痛级测定。随机双盲分4组:①肌注安慰剂,根尖周注射安慰剂;②肌注KT30mg,根尖周注射安慰剂;③肌注安慰剂,根尖周注射KT;④肌注安慰剂,根尖周作2％卡波卡因局麻注射,注射后15,30,45和60min再记录疼痛分值。局麻下行切髓术,嘱回家记录疼痛分值并送回报告。 结果显示根尖周注射KT有显著的牙髓止痛效
Ketorolac tromethamine (KT) is a non-steroidal anti-inflammatory drug used in the United States for intramuscular injection. The aim of this study was to compare the analgesic effect of this drug on pulp pain with periapical and intramuscular injections. The authors selected 52 patients (18 to 65 years) healthy patients with acute pulpitis, each patient received an intramuscular injection of deltoid muscle and adjacent achalasia injection of 1ml 1.8ml peritoneal injection after baseline pain level was determined. Randomly double-blind divided into 4 groups: ① intramuscular placebo, periapical injection placebo; ② intramuscular injection of KT30mg, periapical injection of placebo; ③ intramuscular placebo, periapical injection of KT; ④ intramuscular placebo, Periapical 2% carbachine local anesthesia injection, 15,30,45 and 60min after injection and then record the pain score. Local anesthesia cut the cord, told go home record pain score and sent back the report. The results showed that periapical injection of KT had significant dental pulp analgesia