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目的:观察冻干重组人脑利尿钠肽(rhBNP)治疗急性心力衰竭的疗效。方法:将2009年8月至2011年5月收治的急性心力衰竭患者63例随机分为观察组(n=32)和对照组(n=31),分别在常规治疗的基础上给予rhBNP和硝普钠治疗,比较两组临床疗效和血浆脑利尿钠肽(BNP)浓度。结果:观察组治疗后的各项指标均较对照组明显好转(P均<0.05)。结论:冻干重组人脑利尿肽治疗急性心力衰竭疗效明确,不良反应发生率低。
Objective: To observe the effect of lyophilized recombinant human brain natriuretic peptide (rhBNP) in the treatment of acute heart failure. Methods: 63 patients with acute heart failure who were admitted from August 2009 to May 2011 were randomly divided into observation group (n = 32) and control group (n = 31), and rhBNP Sodium treatment, the clinical efficacy and plasma brain natriuretic peptide (BNP) concentrations were compared. Results: After treatment, the indexes in the observation group were significantly improved compared with the control group (all P <0.05). Conclusion: The lyophilized recombinant human brain diuretic peptide is effective in treating acute heart failure with low incidence of adverse reactions.