随着抗生素的广泛使用 ,耐药菌株已成为引起临床感染较为常见的病原菌。特别是医院内耐药菌株的感染使病死率大幅增加 ,其治疗已成为临床上的难题。现对临床常见耐药菌及抗菌药物研究进展进行简单介绍。1　临床常见耐药菌目前临床常见的重要耐药革兰阳性菌有耐甲氧西林葡萄球菌 With the widespread use of antibiotics, drug-resistant strains have become the more common pathogens causing clinical infections. In particular, the hospital infection caused by drug-resistant strains of a substantial increase in mortality, the treatment has become a clinical problem. Now common clinical drug-resistant bacteria and antimicrobial research progress is briefly introduced. A common clinical drug-resistant bacteria Currently clinically important and important drug-resistant Gram-positive bacteria are methicillin-resistant Staphylococcus aureus