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研究重型肝炎患者血清sCR1浓度的变化 ,探讨其临床意义。采用酶联免疫吸附法 ,对 3 0例重型肝炎、46例慢性病毒性肝炎及 3 0例正常人群红细胞研究表明 ,重型肝炎及慢性病毒性肝炎患者血清sCR1浓度均高于正常对照人群 (P <0 0 1) ,但重型肝炎患者血清sCR1浓度升高的幅度明显大于慢性病毒性肝炎患者 (P <0 0 1) ,并与CHE、PT及PTA的变化明显相关。重型肝炎患者血清sCR1浓度的变化与肝功能损伤程度密切相关 ,该指标可作为分析重型肝炎患者病情严重程度、判断病情发展及预后的重要参考指标
To study the changes of serum sCR1 levels in patients with severe hepatitis and to investigate its clinical significance. Using enzyme-linked immunosorbent assay, 30 cases of severe hepatitis, 46 cases of chronic viral hepatitis and 30 cases of normal population erythrocyte studies have shown that patients with severe hepatitis and chronic viral hepatitis serum sCR1 concentrations were higher than the normal control group (P <0 0 1). However, the serum concentration of sCR1 in patients with severe hepatitis was significantly higher than that in patients with chronic viral hepatitis (P <0.01), and was significantly correlated with the changes of CHE, PT and PTA. Serum levels of sCR1 in patients with severe hepatitis are closely related to the degree of liver injury. This index can be used as an important reference index for analyzing the severity of severe hepatitis patients and judging the progression of disease and prognosis