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1954年保加利亞医学科学院院士教授描寫一种新型的腦炎而命名为儿童亞急性進行性多功性腦炎,此种腦炎的特点是緩慢发病,逐渐出現精神錯乱,有肌攣縮性反射击样的多动,特別表現为扭轉性痙攣,經常出現植物神經異常的症狀,且有癲癇样的发作。椎体路征象不顯,最后逐漸發展成嚴重的恶液質,出現大腦功能衰竭的症狀,一般病程为4-11月,予后不良,死亡率很高,其病理改变;主要在脑皮層,底節,桥腦及下橄欖核,小腦改变極輕。
1954 Professor of the Bulgarian Academy of Medical Sciences describes a new type of encephalitis and named subacute progressive polyneuritis in children, the encephalitis is characterized by the slow onset, the gradual emergence of insanity, muscle contracture reflex shot The hyperactivity, especially for torsion spasm, often appear symptoms of autonomic dysfunction, and epileptic seizures. The signs of vertebral body pathology is not significant, and finally gradually developed into severe cachexia, brain failure symptoms appear, the general course of 4-11 months, poor prognosis, high mortality, the pathological changes; mainly in the cortex, Bottom section, pons and olivary nuclei, cerebellar changes very light.