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分析原发性醛固酮增多症(PA)49例,其中肾上腺腺瘤(APA)39例(79.6%),肾上腺增生10例(20.4%),主要症状为高血压、低血钾;47例血钾低于正常,29例血浆醛固酮测定高于正常值,25例作安体舒通试验,其中22例有血压下降、血钾增高。采用高分辨度、层距为2~4mmCT连续扫描,其确诊率达95.0%。结果39例APA患者和6例肾上腺增生者术后血压、血钾均恢复正常,4例肾上腺增生患者半年后仍需用药物控制血压。并对PA的诊断、手术途径及治疗进行了讨论,认为B超和CT是诊断PA的主要诊断方法,开放手术仍是主要的治疗手段,而腹腔镜肾上腺切除术是一种很有前途的治疗方法。
Forty - nine patients with primary aldosteronism (PA) were analyzed. Among them, 39 (79.6%) had adrenal adenoma (APA) and 10 (20.4%) had adrenal hyperplasia. The main symptoms were hypertension and hypokalemia. 47 cases of serum potassium lower than normal, 29 cases of plasma aldosterone measured higher than normal, 25 cases of spironolactone test, of which 22 cases of blood pressure, elevated serum potassium. Using high resolution, layer spacing of 2 ~ 4mmCT continuous scan, the diagnosis rate of 95.0%. Results The blood pressure and blood potassium of 39 patients with APA and 6 patients with adrenal hyperplasia returned to normal. Four patients with adrenal hyperplasia still needed medication to control blood pressure after six months. And the diagnosis of PA, surgical approach and treatment were discussed, that B-and CT is the main diagnostic method of diagnosis of PA, open surgery is still the main treatment, and laparoscopic adrenalectomy is a promising treatment method.