一百年以前,Benedikt合成了四溴环酮。但一直到1971年,Calo等人将四溴环酮用于酚类化物的选择性溴化,才引起人们的注意。经过最近几年的探索,逐渐发现四溴环酮在有机合成上有着非常广阔的用途。它不但可以用作酚、芳胺、烯和多烯、不饱和醇、不饱和酮、甾体、含氮杂环等化合物的新型选择性溴化剂,还可用作含硫化物和某些金属化物的氧化剂以及一些聚合 One hundred years ago, Benedikt synthesized tetrabromoketone. However, it was not until 1971 that Calo et al. Used tetrabromoketone for the selective bromination of phenols. After the exploration in recent years, it has gradually been found that tetrabromoketone has a very wide range of uses in organic synthesis. It can be used not only as a new selective brominating agent for phenols, aromatic amines, alkenes and polyenes, unsaturated alcohols, unsaturated ketones, steroids, nitrogen-containing heterocycles and other compounds, but also for sulphides and certain Oxides of metallides and some polymerizations