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目的 探讨皮肤交感电反应 (SSR)与慢性乙醇中毒自主神经系统交感神经病变的关系 ,为慢性乙醇中毒自主神经系统病变的早期诊断提供客观依据。方法 对 5 0例慢性乙醇中毒患者进行SSR的检测 ,并与 4 0例正常人进行对比分析。结果 慢性乙醇中毒组SSR潜伏期显著延长 (P <0 .0 0 1) ,患者的饮酒年限、饮酒量与SSR呈正相关。结论 SSR为慢性乙醇中毒自主神经系统交感神经病变的早期诊断提供了新的方法依据 ,可作为评价慢性乙醇中毒自主神经系统交感神经纤维的早期病变的客观电生理指标。
Objective To investigate the relationship between the skin sympathetic response (SSR) and autonomic nervous system sympathetic neuropathy in patients with chronic alcoholism and provide an objective basis for the early diagnosis of chronic alcoholism-induced autonomic nervous system diseases. Methods Fifty patients with chronic alcoholism were tested for SSR and compared with 40 healthy controls. Results The SSR latency was significantly prolonged in chronic alcoholism group (P <0.01). The drinking duration and alcohol consumption of patients with chronic alcoholism were positively correlated with SSR. Conclusion SSR provides a new method for the early diagnosis of sympathetic neuropathy in chronic alcoholism. It can be used as an objective electrophysiological index to evaluate the early lesions of sympathetic nerve fibers of chronic alcoholism with autonomic nervous system.