界面活性物质,是目前基层药剂工作中经常使用的一大类物质。近五十年来,这类物质的发展突飞猛进。在药剂工作中,特别是基层药剂工作中的应用日益广泛。因此,为了普及这方面的基本知识,现对其基本原理,以及在药剂工作中的使用情况及某些注意事项加以简要介绍。界面活性物质的基本概念一、什么是界面活性物质?如果我们把某些物质溶解于溶剂(一般指水),而能显著降低溶剂(一般指水)的界面张力,那么这些物质就叫做“界面活性物质”。如常用的肥皂、软皂、羧甲基纤维素钠、新洁而灭、吐温—80等都是界面活性物质。二、什么是界面张力与界面自由能? (一)表面张力与界面张力:如将一般 Interface active substances, is currently a major category of substances commonly used in the work of primary pharmaceuticals. In the past 50 years, the development of such materials has been advancing by leaps and bounds. In pharmaceutical work, especially the application of primary pharmaceutical work is increasingly widespread. Therefore, in order to popularize the basic knowledge in this field, its basic principle, its use in pharmaceutical preparations and some precautions are briefly introduced. Basic Concepts of Interface Actives 1. What is an interface active? If we dissolve some of the substances in a solvent (generally water) and significantly reduce the interfacial tension of the solvent (generally water), then these are called interfaces Active substance ". Such as soap, soft soap, sodium carboxymethyl cellulose, the new Jie and off, Tween -80 are all interface active substances. Second, what is the interfacial tension and interface free energy? (A) the surface tension and interfacial tension: as will be general