作者综述了Ⅲ型肺炎链球菌荚膜多糖(SSS-Ⅲ)引起的抗体应答中抑制性T(Ts)细胞和放大性T(Ta)细胞的免疫调节作用、Ts和Ta细胞激活的机理、Ts和Ta细胞功能成熟的时间差异,阐述了单磷酸脂蛋白A(MPL)免疫佐剂作用的机理及其实际应用价值。 The authors reviewed the immunomodulatory effects of suppressive T (Ts) cells and magnifying T (Ta) cells on antibody responses induced by Streptococcus pneumoniae capsular polysaccharide (SSS-III), the mechanism of Ts and Ta cell activation, Ts And Ta cell function maturation time differences, elaborated the monophosphate lipoprotein A (MPL) immune adjuvant mechanism and its practical value.