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随着经济水平的提高,全球老龄化现象的日渐加剧,减少老年人慢性病发病率,提高社会的整体生活质量,是当今医学工作者着力研究的重点。成年后的机体在细胞、组织以及器官等各方面都存在不同程度的不可逆转性。“胎源假说”认为生命早期营养不良与成年后患代谢综合征(metabolic syndrome,MS)关系密切,如果在生命早期就采取干预措施,应该能够减少或避免成年后一系列疾病的发生。因此,本文就生命早期营养不良与MS各组分(肥胖、高血糖、高血压及高血脂等)的关系作一综述。
With the improvement of economic level, the phenomenon of global aging is aggravating day by day, reducing the incidence of chronic diseases in the elderly and improving the overall quality of life of the community are the focuses of medical workers today. Adult body in the cells, tissues and organs and other aspects there are varying degrees of irreversibility. The “fetal origin hypothesis” believes that early malnutrition is closely related to metabolic syndrome (MS) in adulthood. If interventions are taken early in life, it should be able to reduce or avoid a series of diseases in adulthood. Therefore, this article reviews the relationship between early malnutrition and various MS components (obesity, hyperglycemia, hypertension and hyperlipidemia) in early life.