甲状腺功能异常对孕妇及妊娠结局的影响

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目的探讨甲状腺功能异常对于妇女妊娠结局的影响。方法择选我院2014年1月至2016年6月收诊并通过甲状腺功能筛查确诊为甲状腺功能异常的70例待产孕妇作为甲状腺异常的研究组,于此同时与我院同期收诊的甲状腺功能处于正常良好状态的孕妇85例作为对照组。对两组孕妇在妊娠期间的临床表现进行及时的监测对比分析,在分娩结束后的3周内进行相应的回访调查,通过观测比较妊娠期临床数据与最后的妊娠结局来获得结论。结果在对两组孕妇进行监测观察期间,发现就妊娠期并发症如妊高症、贫血、糖尿病等的综合发生概率来看,对照组较研究组的发病率较低,而在早产,流产和死胎的发生概率上,对照组同样低于研究组,并且在完成分娩之后对新生儿进行的体重检测上,甲状腺功能异常的研究组呈现出较高的新生儿低体质量概率,两组间对比的差异具有统计学意义(即P<0.05),研究组与对照组间的孕妇胎盘早剥现象和胎儿窘迫的发生概率则与所参考的甲状腺功能是否异常方面无明显的差异,结果并无统计学意义(P>0.05)。结论甲状腺功能异常对于孕妇和妊娠结局都有不良的影响,且在孕期的并发症较多,应尽量对甲状腺功能进行控制,确保其在正常水平范围内,对母婴安全进行保障。 Objective To investigate the effect of abnormal thyroid function on pregnancy outcome in women. Methods Seventy cases of pregnant women who were admitted to our hospital from January 2014 to June 2016 and were diagnosed as thyroid dysfunction by thyroid function screening were selected as the study group of thyroid abnormality. At the same time, with the thyroid 85 cases of pregnant women with normal functioning status served as control group. The two groups of pregnant women in clinical performance during pregnancy, timely monitoring and comparative analysis of the three weeks after the end of delivery, the corresponding return visit survey by observing the clinical data during pregnancy and the final pregnancy outcome to draw conclusions. Results During monitoring and observation of two groups of pregnant women, it was found that the morbidity of pregnancy complications such as pregnancy-induced hypertension, anemia and diabetes were lower in the control group than in the study group, while in preterm birth, miscarriage and stillbirth , The control group was also lower than the study group, and on the weight test of the newborn after completion of delivery, the study group with abnormal thyroid function showed a higher probability of low body weight of the newborn, the difference between the two groups (P <0.05). There was no significant difference in the incidence of placental abruption and the incidence of fetal distress between the study group and the control group in terms of whether the thyroid function was abnormal or not, and the result was not statistically significant Significance (P> 0.05). Conclusions Thyroid dysfunction has adverse effects on pregnant women and pregnancy outcomes, and more complications during pregnancy. Thyroid function should be controlled as far as possible to ensure its safety within the normal range.
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