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染色体病的发病率约占新生儿的1/160~200,活婴中罗式易位频率约为1‰。人的5对近端着丝粒染色体可以出现15种不同类型的罗伯逊易位,其中D/D 易位最为常见,而在D/D 类型中,13/14易位又最常见。我院5年来,接待遗传咨询门诊4671人次。产前诊断及羊水细胞培养1000余例,其中发现一例一家三代4例平衡易位。孕妇××,因怀孕一个多月时患病毒性感冒,工作中又接触苯及氯仿等,于妊娠5个月时前来遗传咨询门诊,要求产前诊断抽羊水检查。羊水细胞培养按
The incidence of chromosome disease accounted for about 1/160 ~ 200 newborns, live baby Carole translocation frequency of about 1 ‰. Fifteen different types of Robertson translocations can occur in five pairs of proximal centromere chromosomes, of which D / D translocations are the most common, whereas in D / D type, 13/14 translocations are the most common. Our hospital 5 years, 4671 people received genetic counseling clinic. Prenatal diagnosis and amniotic fluid cell culture of more than 1,000 cases, of which found a case of three generations of 4 cases of balanced translocation. Pregnant women × ×, because of pregnancy more than a month when suffering from viral influenza, and work in contact with benzene and chloroform, etc., at 5 months of gestation to genetic counseling clinic, requiring prenatal diagnosis of amniotic fluid check. Amniotic fluid cell culture press