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目的了解山东省首例W135群流行性脑脊髓膜炎病例发病特点和流行病学特征,及时了解历城区流脑菌群变迁动向。方法查阅病例病案,开展流行病学调查,采集病例及密切接触者相关标本进行实验室检测。结果病例急起高热、头痛、呕吐、四肢抽搐、上肢及右中腹出现散在出血点、晕厥、昏迷等,于2014年1月18日死亡。曾有4次A群流脑疫苗免疫史,本次发病前无流脑和疑似病例病例接触史。病例标本经山东省疾控中心检测为脑膜炎奈瑟菌W135群。结论该病例为山东省首例W135群流行性脑脊髓膜炎病例。
Objective To understand the onset and epidemiological characteristics of the first case of W135 epidemic meningitis in Shandong Province and to keep abreast of the trends of the evolution of meningococci in Licheng District. Methods Access to medical records, epidemiological investigation, collection of cases and close contact specimens for laboratory testing. Results The patient died of fever, headache, vomiting, convulsions on the limbs, scattered bleeding in the upper extremities and the right middle abdomen, syncope and coma on January 18, 2014. There have been 4 times A group of meningitis vaccine immunization history, before the onset of no meningitis and suspected case history of exposure. Case specimens were tested by the CDC in Shandong Province as Neisseria meningitidis W135 group. Conclusion This case is the first case of W135 epidemic cerebrospinal meningitis in Shandong Province.