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目的根据WHO糖尿病诊断和分类委员会近来提出的糖尿病新诊断标准中以空腹血糖(FPG)≥7.0mmol/L(≥126mg/dl)取代FPG≥7.8mmol/L(≥140mg/dl),为探讨我国糖尿病人群FPG的诊断水平。方法对1994年全国25岁以上25万人群糖尿病普查中经口服75g葡萄糖耐量试验(OGTT)检查人群的资料进行了分析(其中新诊断2型糖尿病2380例、糖耐量低减3106例、OGTT正常7725例、共13211例)。结果经FPG分布频数发现,在新诊断糖尿病组中约50%的人FPG<7.8mmol/L。在该组经直线回归分析显示:与OGTT后2小时静脉血浆血糖(PG2h)≥11.1mmol/L(≥200mg/dl)相关最好的FPG值是≥6.7mmol/L(≥121mg/dl)(P<0.0001)。与WHO提出的FPG≥7.0mmol/L非常接近。经检验FPG≥7.0mmol/L(≥126mg/dl)的特异性好于FPG≥6.7mmol/L(分别为95%和91%),敏感性好于FPG≥7.8mmol/L(分别为67%和53%),提示FPG≥7.8mmol/L不是一个灵敏的诊断指标。在总受检人群组13211例经?
Objective According to the new diagnostic criteria of diabetes newly proposed by the WHO Committee on Diabetes Diagnosis and Classification, FPG≥7.0mmol / L (≥126mg / dl) was substituted for FPG≥7.8mmol / L (≥140mg / dl) To explore the diagnosis of FPG in diabetic population in China. Methods The data of 75 patients with oral glucose tolerance test (OGTT) in the survey of 250 000 population over 25 years of age in China in 1994 were analyzed (including 2380 cases of newly diagnosed type 2 diabetes, 3106 cases of impaired glucose tolerance and 7725 cases of normal OGTT Cases, a total of 13211 cases). Results The frequency of FPG distribution was found in approximately 50% of the newly diagnosed diabetic patients FPG <7.8mmol / L. Linear regression analysis in this group showed that the best FPG value associated with a PG2h of ≥11.1 mmol / L (≥200 mg / dl) at 2 hours after OGTT was ≥ 6.7 mmol / L (≥ 121 mg / dl ) (P <0.0001). And WHO proposed FPG ≥ 7.0mmol / L very close. The test FPG≥7.0mmol / L (≥126mg / dl) specificity is better than FPG≥6.7mmol / L (95% and 91% respectively), the sensitivity is better than FPG≥7.8mmol / L 67% and 53%), suggesting that FPG ≥ 7.8mmol / L is not a sensitive diagnostic indicator. In the total subjects 132 132 cases?