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目的观察卡介菌多糖核酸注射液治疗儿童反复呼吸道感染(RRI)的临床疗效及血清免疫球蛋白水平的影响.方法将154例反复呼吸道感染患儿,随机分为两组,治疗组90例,对照组64例,50例因各种原因退出观察,完成观察的病例中,治疗组54例,对照组50例共计105例,对照组常规给予抗感染及对症治疗;治疗组在常规治疗外,加卡介菌多糖核酸注射液1ml/次,每周2次,连用12周;观察记录临床疗效及治疗前后IgG、IgA、IgM水平结果治疗组治疗后RRI发作次数明显减少;血清IgG、IgA水平提高.结论卡介菌多糖核酸注射液对治疗反复呼吸道感染有明显疗效.
Objective To observe the effect of BCG-polysaccharide nucleic acid injection on children with recurrent respiratory tract infection (RRI) and the effect of serum immunoglobulin.Methods 154 children with recurrent respiratory tract infection were randomly divided into two groups, the treatment group 90 cases, The control group of 64 patients, 50 patients withdraw from the observation for various reasons, the completion of observation cases, the treatment group 54 cases, the control group of 50 cases a total of 105 cases, the control group conventional anti-infective and symptomatic treatment; treatment group in the conventional treatment, Plus BCG polysaccharide nucleic acid injection 1ml / time, twice a week for 12 weeks; observed and recorded the clinical efficacy and treatment before and after the results of IgG, IgA, IgM results in the treatment group, the number of RRI seizures decreased significantly; serum IgG, IgA levels Improve.Conclusion BCG polysaccharide nucleic acid injection for the treatment of recurrent respiratory tract infection has a significant effect.